BDBM256138 US9487462, 20
SMILES: CCOC(=O)c1csc(CN(Cc2ccncc2)Cc2ccc(OCc3ccccc3)cc2)n1
InChI Key: InChIKey=OOJBMOGUJOIIKR-UHFFFAOYSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM256138 (US9487462, 20) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 37 |
PharmaHungary 2000 Kft.; TargetEx Kft. US Patent | Assay Description Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as... | US Patent US9487462 (2016) BindingDB Entry DOI: 10.7270/Q2W094VZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interstitial collagenase (Homo sapiens (Human)) | BDBM256138 (US9487462, 20) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.25E+5 | n/a | n/a | n/a | n/a | 7.5 | 37 |
PharmaHungary 2000 Kft.; TargetEx Kft. US Patent | Assay Description Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as... | US Patent US9487462 (2016) BindingDB Entry DOI: 10.7270/Q2W094VZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Collagenase 3 (Homo sapiens (Human)) | BDBM256138 (US9487462, 20) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | 7.5 | 37 |
PharmaHungary 2000 Kft.; TargetEx Kft. US Patent | Assay Description Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as... | US Patent US9487462 (2016) BindingDB Entry DOI: 10.7270/Q2W094VZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Matrix metalloproteinase-9 (Homo sapiens (Human)) | BDBM256138 (US9487462, 20) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 37 |
PharmaHungary 2000 Kft.; TargetEx Kft. US Patent | Assay Description Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as... | US Patent US9487462 (2016) BindingDB Entry DOI: 10.7270/Q2W094VZ | |||||||||||
More data for this Ligand-Target Pair |