BDBM256277 US9487488, 1
SMILES: FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cc2)-c2nnn[nH]2)cc1
InChI Key: InChIKey=HLLKNPAVDRASLS-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily M member 8 (TRPM8) (Homo sapiens (Human)) | BDBM256277 (US9487488, 1) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | 37 |
MITSUBISHI TANABE PHARMA CORPORATION US Patent | Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore... | US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT | |||||||||||
More data for this Ligand-Target Pair |