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SMILES: FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cc2)-c2ncn[nH]2)cc1

InChI Key: InChIKey=ILGZTZIIQZVACZ-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 256281   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM256281
PNG
(US9487488, 5)
Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cc2)-c2ncn[nH]2)cc1
Show InChI InChI=1S/C28H22F3N5O3S/c29-28(30,31)39-22-11-5-18(6-12-22)16-36(27-25(19-7-8-19)24-4-2-1-3-21(24)15-32-27)40(37,38)23-13-9-20(10-14-23)26-33-17-34-35-26/h1-6,9-15,17,19H,7-8,16H2,(H,33,34,35)
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PC cid
PC sid
UniChem
US Patent
n/an/a 3.40n/an/an/an/an/a37



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...

US Patent US9487488 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NGT
More data for this
Ligand-Target Pair