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SMILES: FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(nc2)-c2ncn[nH]2)cc1

InChI Key: InChIKey=UDWMKNZNZCLCTN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 256282   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM256282
PNG
(US9487488, 6)
Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(nc2)-c2ncn[nH]2)cc1
Show InChI InChI=1S/C27H21F3N6O3S/c28-27(29,30)39-20-9-5-17(6-10-20)15-36(26-24(18-7-8-18)22-4-2-1-3-19(22)13-32-26)40(37,38)21-11-12-23(31-14-21)25-33-16-34-35-25/h1-6,9-14,16,18H,7-8,15H2,(H,33,34,35)
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PC cid
PC sid
UniChem
US Patent
n/an/a 1.70n/an/an/an/an/a37



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...

US Patent US9487488 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NGT
More data for this
Ligand-Target Pair