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SMILES: FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(nc2)-c2noc(=O)[nH]2)cc1

InChI Key: InChIKey=FKKOZLFRPQTHTI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 256285   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM256285
PNG
(US9487488, 9)
Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(nc2)-c2noc(=O)[nH]2)cc1
Show InChI InChI=1S/C27H20F3N5O5S/c28-27(29,30)39-19-9-5-16(6-10-19)15-35(25-23(17-7-8-17)21-4-2-1-3-18(21)13-32-25)41(37,38)20-11-12-22(31-14-20)24-33-26(36)40-34-24/h1-6,9-14,17H,7-8,15H2,(H,33,34,36)
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 1.10n/an/an/an/an/a37



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...

US Patent US9487488 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NGT
More data for this
Ligand-Target Pair