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SMILES: FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C(F)(F)F)S(=O)(=O)c2ccc(cc2)-c2nnn[nH]2)cc1

InChI Key: InChIKey=NPMLMXWIKUQBMO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 256291   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM256291
PNG
(US9487488, 15)
Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C(F)(F)F)S(=O)(=O)c2ccc(cc2)-c2nnn[nH]2)cc1
Show InChI InChI=1S/C25H16F6N6O3S/c26-24(27,28)21-20-4-2-1-3-17(20)13-32-23(21)37(14-15-5-9-18(10-6-15)40-25(29,30)31)41(38,39)19-11-7-16(8-12-19)22-33-35-36-34-22/h1-13H,14H2,(H,33,34,35,36)
PDB

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PC cid
PC sid
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US Patent
n/an/a 2n/an/an/an/an/a37



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...

US Patent US9487488 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NGT
More data for this
Ligand-Target Pair