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SMILES: Cc1cc(ccc1-c1ncn[nH]1)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1

InChI Key: InChIKey=NIPDOKDFDYTSMD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 256299   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM256299
PNG
(US9487488, 23)
Show SMILES Cc1cc(ccc1-c1ncn[nH]1)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1
Show InChI InChI=1S/C29H24F3N5O3S/c1-18-14-23(12-13-24(18)27-34-17-35-36-27)41(38,39)37(16-19-6-10-22(11-7-19)40-29(30,31)32)28-26(20-8-9-20)25-5-3-2-4-21(25)15-33-28/h2-7,10-15,17,20H,8-9,16H2,1H3,(H,34,35,36)
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PC cid
PC sid
UniChem
US Patent
n/an/a 0.5n/an/an/an/an/a37



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...

US Patent US9487488 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NGT
More data for this
Ligand-Target Pair