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SMILES: FC(F)(F)c1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cc2)-c2ncn[nH]2)nc1

InChI Key: InChIKey=XNRXEXPHJJGLLN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 256300   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM256300
PNG
(US9487488, 24)
Show SMILES FC(F)(F)c1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cc2)-c2ncn[nH]2)nc1
Show InChI InChI=1S/C27H21F3N6O2S/c28-27(29,30)20-9-10-21(31-14-20)15-36(26-24(17-5-6-17)23-4-2-1-3-19(23)13-32-26)39(37,38)22-11-7-18(8-12-22)25-33-16-34-35-25/h1-4,7-14,16-17H,5-6,15H2,(H,33,34,35)
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PC cid
PC sid
UniChem
US Patent
n/an/a 1.20n/an/an/an/an/a37



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...

US Patent US9487488 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NGT
More data for this
Ligand-Target Pair