BindingDB logo
myBDB logout

null

SMILES: FC(F)(F)c1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cc2)-c2noc(=O)[nH]2)nc1

InChI Key: InChIKey=UTSFDPFAAXWAOC-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 256307   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM256307
PNG
(US9487488, 31)
Show SMILES FC(F)(F)c1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cc2)-c2noc(=O)[nH]2)nc1
Show InChI InChI=1S/C27H20F3N5O4S/c28-27(29,30)19-9-10-20(31-14-19)15-35(25-23(16-5-6-16)22-4-2-1-3-18(22)13-32-25)40(37,38)21-11-7-17(8-12-21)24-33-26(36)39-34-24/h1-4,7-14,16H,5-6,15H2,(H,33,34,36)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.10n/an/an/an/an/a37



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...

US Patent US9487488 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NGT
More data for this
Ligand-Target Pair