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SMILES: Cc1cc(ccc1S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1)C(O)=O

InChI Key: InChIKey=BQXRJPCGDGMUFY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 256314   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM256314
PNG
(US9487488, 38)
Show SMILES Cc1cc(ccc1S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1)C(O)=O
Show InChI InChI=1S/C28H23F3N2O5S/c1-17-14-20(27(34)35)10-13-24(17)39(36,37)33(16-18-6-11-22(12-7-18)38-28(29,30)31)26-25(19-8-9-19)23-5-3-2-4-21(23)15-32-26/h2-7,10-15,19H,8-9,16H2,1H3,(H,34,35)
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 0.700n/an/an/an/an/a37



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...

US Patent US9487488 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NGT
More data for this
Ligand-Target Pair