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SMILES: Cc1cc(ccc1C(O)=O)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1nc(C2CC2)c2ccccc2c1C

InChI Key: InChIKey=ZJIPNYXNUTYVLN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 256316   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM256316
PNG
(US9487488, 40)
Show SMILES Cc1cc(ccc1C(O)=O)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1nc(C2CC2)c2ccccc2c1C
Show InChI InChI=1S/C29H25F3N2O5S/c1-17-15-22(13-14-23(17)28(35)36)40(37,38)34(16-19-7-11-21(12-8-19)39-29(30,31)32)27-18(2)24-5-3-4-6-25(24)26(33-27)20-9-10-20/h3-8,11-15,20H,9-10,16H2,1-2H3,(H,35,36)
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 6.5n/an/an/an/an/a37



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...

US Patent US9487488 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NGT
More data for this
Ligand-Target Pair