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SMILES: Cc1cc(cc(F)c1C(O)=O)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1

InChI Key: InChIKey=LDIAWFSMNMYGLY-UHFFFAOYSA-N

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 256318   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM256318
PNG
(US9487488, 42)
Show SMILES Cc1cc(cc(F)c1C(O)=O)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1
Show InChI InChI=1S/C28H22F4N2O5S/c1-16-12-21(13-23(29)24(16)27(35)36)40(37,38)34(15-17-6-10-20(11-7-17)39-28(30,31)32)26-25(18-8-9-18)22-5-3-2-4-19(22)14-33-26/h2-7,10-14,18H,8-9,15H2,1H3,(H,35,36)
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PC cid
PC sid
UniChem
US Patent
n/an/a 1.5n/an/an/an/an/a37



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...

US Patent US9487488 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NGT
More data for this
Ligand-Target Pair