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SMILES: CN(C)c1cc(ccc1C(O)=O)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1

InChI Key: InChIKey=RQCLPFJQKXRUIJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 256321   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM256321
PNG
(US9487488, 45)
Show SMILES CN(C)c1cc(ccc1C(O)=O)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1
Show InChI InChI=1S/C29H26F3N3O5S/c1-34(2)25-15-22(13-14-24(25)28(36)37)41(38,39)35(17-18-7-11-21(12-8-18)40-29(30,31)32)27-26(19-9-10-19)23-6-4-3-5-20(23)16-33-27/h3-8,11-16,19H,9-10,17H2,1-2H3,(H,36,37)
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 2.90n/an/an/an/an/a37



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...

US Patent US9487488 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NGT
More data for this
Ligand-Target Pair