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SMILES: CCc1cc(ccc1C(O)=O)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C(F)(F)F

InChI Key: InChIKey=ZUBGCRKDESFGFT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 256329   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM256329
PNG
(US9487488, 53)
Show SMILES CCc1cc(ccc1C(O)=O)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C(F)(F)F
Show InChI InChI=1S/C27H20F6N2O5S/c1-2-17-13-20(11-12-22(17)25(36)37)41(38,39)35(15-16-7-9-19(10-8-16)40-27(31,32)33)24-23(26(28,29)30)21-6-4-3-5-18(21)14-34-24/h3-14H,2,15H2,1H3,(H,36,37)
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 3n/an/an/an/an/a37



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...

US Patent US9487488 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NGT
More data for this
Ligand-Target Pair