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SMILES: OC(=O)c1ccc(cc1N1CCCC1)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1

InChI Key: InChIKey=FBKYYYFJHORFQQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 256334   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM256334
PNG
(US9487488, 58)
Show SMILES OC(=O)c1ccc(cc1N1CCCC1)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1
Show InChI InChI=1S/C31H28F3N3O5S/c32-31(33,34)42-23-11-7-20(8-12-23)19-37(29-28(21-9-10-21)25-6-2-1-5-22(25)18-35-29)43(40,41)24-13-14-26(30(38)39)27(17-24)36-15-3-4-16-36/h1-2,5-8,11-14,17-18,21H,3-4,9-10,15-16,19H2,(H,38,39)
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PC cid
PC sid
UniChem
US Patent
n/an/a 4.60n/an/an/an/an/a37



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...

US Patent US9487488 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NGT
More data for this
Ligand-Target Pair