BDBM256457 US9487512, 1
SMILES: C1C(NC2CCNCC2)[C@H]1c1ccccc1
InChI Key: InChIKey=BASFYRLYJAZPPL-KWCCSABGSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutathione S-transferase P/Isoform 2 of Lysine-specific histone demethylase 1A (2) [158-876] (Homo sapiens (Human)) | BDBM256457 (US9487512, 1) | PDB UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 50 | -10.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Oryzon Genomics S.A. US Patent | Assay Description The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ... | US Patent US9487512 (2016) BindingDB Entry DOI: 10.7270/Q2765D89 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM256457 (US9487512, 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | >1.00E+5 | >-5.67 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oryzon Genomics S.A. US Patent | Assay Description Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s... | US Patent US9487512 (2016) BindingDB Entry DOI: 10.7270/Q2765D89 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM256457 (US9487512, 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | >1.00E+5 | >-5.67 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oryzon Genomics S.A. US Patent | Assay Description Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s... | US Patent US9487512 (2016) BindingDB Entry DOI: 10.7270/Q2765D89 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathione S-transferase P/Isoform 2 of Lysine-specific histone demethylase 1A (2) [158-876] (Homo sapiens (Human)) | BDBM256457 (US9487512, 1) | PDB UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 56 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Oryzon Genomics S.A. US Patent | Assay Description The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ... | US Patent US9487512 (2016) BindingDB Entry DOI: 10.7270/Q2765D89 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM256457 (US9487512, 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oryzon Genomics S.A. US Patent | Assay Description Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s... | US Patent US9487512 (2016) BindingDB Entry DOI: 10.7270/Q2765D89 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM256457 (US9487512, 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oryzon Genomics S.A. US Patent | Assay Description Human recombinant monoamine oxidase proteins MAO-A and MAO-B were purchased from Sigma Aldrich. MAOs catalyze the oxidative deamination of primary, s... | US Patent US9487512 (2016) BindingDB Entry DOI: 10.7270/Q2765D89 | |||||||||||
More data for this Ligand-Target Pair |