BDBM258784 US9499482, 190

SMILES: CC1(O)CN(CCOc2ccc(cc2OC(F)F)N2CC=C(Oc3ccc(cc3)C3CC3)C2=O)C1

InChI Key: InChIKey=RUTCPTOYKOQQFW-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 258784   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (MCHR1)(E4Q)(A5T) (Homo sapiens (Human))	BDBM258784 (US9499482, 190) Show SMILES CC1(O)CN(CCOc2ccc(cc2OC(F)F)N2CC=C(Oc3ccc(cc3)C3CC3)C2=O)C1 |t:21| Show InChI InChI=1S/C26H28F2N2O5/c1-26(32)15-29(16-26)12-13-33-21-9-6-19(14-23(21)35-25(27)28)30-11-10-22(24(30)31)34-20-7-4-18(5-8-20)17-2-3-17/h4-10,14,17,25,32H,2-3,11-13,15-16H2,1H3	GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.600	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Company US Patent					Assay Description An in vitro binding assay was used to determine the compound Ki value or ability to antagonize binding of a peptide agonist to the human melanin conc...				US Patent US9499482 (2016) BindingDB Entry DOI: 10.7270/Q2M907KT
					More data for this Ligand-Target Pair