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SMILES: N[C@H]1CCCC[C@H]1Nc1ncc(C(N)=O)c(Nc2ccc3CCN(Cc3c2)C(=O)c2ccccc2O)n1

InChI Key: InChIKey=IXWRPQSMEGDSBW-FCHUYYIVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 260733   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))		BDBM260733
PNG
(US9533989, 43)
Show SMILES N[C@H]1CCCC[C@H]1Nc1ncc(C(N)=O)c(Nc2ccc3CCN(Cc3c2)C(=O)c2ccccc2O)n1
Show InChI InChI=1S/C27H31N7O3/c28-21-6-2-3-7-22(21)32-27-30-14-20(24(29)36)25(33-27)31-18-10-9-16-11-12-34(15-17(16)13-18)26(37)19-5-1-4-8-23(19)35/h1,4-5,8-10,13-14,21-22,35H,2-3,6-7,11-12,15,28H2,(H2,29,36)(H2,30,31,32,33)/t21-,22+/m0/s1
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PC cid
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US Patent
n/an/a 15.9n/an/an/an/an/an/a



Ziarco Pharma Ltd.

US Patent


Assay Description
The Promega ADP-Glo Kinase Assay is a luminescent ADP detection assay that provides a universal, homogeneous, high-throughput screening method to mea...

US Patent US9533989 (2017)


BindingDB Entry DOI: 10.7270/Q2VQ31M7
More data for this
Ligand-Target Pair