BDBM260787 US9533989, 98

SMILES: N[C@H]1CCCC[C@H]1Nc1ncc(C(N)=O)c(Nc2cccc(Sc3cccc(O)c3)c2)n1

InChI Key: InChIKey=MFRGFVISHWMXKF-VQTJNVASSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 260787   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM260787 (US9533989, 98) Show SMILES N[C@H]1CCCC[C@H]1Nc1ncc(C(N)=O)c(Nc2cccc(Sc3cccc(O)c3)c2)n1 Show InChI InChI=1S/C23H26N6O2S/c24-19-9-1-2-10-20(19)28-23-26-13-18(21(25)31)22(29-23)27-14-5-3-7-16(11-14)32-17-8-4-6-15(30)12-17/h3-8,11-13,19-20,30H,1-2,9-10,24H2,(H2,25,31)(H2,26,27,28,29)/t19-,20+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	72.9	n/a	n/a	n/a	n/a	n/a	n/a
Ziarco Pharma Ltd. US Patent					Assay Description The Promega ADP-Glo Kinase Assay is a luminescent ADP detection assay that provides a universal, homogeneous, high-throughput screening method to mea...				US Patent US9533989 (2017) BindingDB Entry DOI: 10.7270/Q2VQ31M7
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