BDBM260796 US9533989, 107

SMILES: COc1cc(Nc2nc(N[C@@H]3CCCC[C@@H]3N)n3ccnc3c2C(N)=O)ccc1-c1cccc(C)c1

InChI Key: InChIKey=JYBPOJMQEGWHEX-LEWJYISDSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 260796   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM260796 (US9533989, 107) Show SMILES COc1cc(Nc2nc(N[C@@H]3CCCC[C@@H]3N)n3ccnc3c2C(N)=O)ccc1-c1cccc(C)c1 Show InChI InChI=1S/C27H31N7O2/c1-16-6-5-7-17(14-16)19-11-10-18(15-22(19)36-2)31-25-23(24(29)35)26-30-12-13-34(26)27(33-25)32-21-9-4-3-8-20(21)28/h5-7,10-15,20-21,31H,3-4,8-9,28H2,1-2H3,(H2,29,35)(H,32,33)/t20-,21+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Ziarco Pharma Ltd. US Patent					Assay Description The Promega ADP-Glo Kinase Assay is a luminescent ADP detection assay that provides a universal, homogeneous, high-throughput screening method to mea...				US Patent US9533989 (2017) BindingDB Entry DOI: 10.7270/Q2VQ31M7
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