BDBM263078 US9708359, 71
SMILES: Cc1nc(N)c2c(cn([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)c2n1)C(N)=O
InChI Key: InChIKey=WLCTVUNWTINQMW-HTVVRFAVSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Norovirus Polymerase (Murine norovirus 1) | BDBM263078 (US9708359, 71) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 3.15E+3 | n/a | n/a | n/a | n/a |
Chimerix, Inc.; The Regents of the University of Michigan US Patent | Assay Description Polymerase reactions (10 μL) were conducted for 60 minutes at 37° C. Nucleoside triphosphates (NTPs) were present at 100 μM each, with 0.05... | US Patent US9708359 (2017) BindingDB Entry DOI: 10.7270/Q22F7QGB | |||||||||||
More data for this Ligand-Target Pair |