BDBM263084 US9708359, 133

SMILES: CC(C)OC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@H]([C@H](OC(=O)C(C)C)[C@@H]1OC(=O)C(C)C)n1cc(C(N)=O)c2c(N)nc(C)nc12)Oc1ccccc1

InChI Key: InChIKey=QAAYUMSCMMVQRH-PLXFLFGQSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 263084   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Norovirus Polymerase (Murine norovirus 1)	BDBM263084 (US9708359, 133) Show SMILES CC(C)OC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@H]([C@H](OC(=O)C(C)C)[C@@H]1OC(=O)C(C)C)n1cc(C(N)=O)c2c(N)nc(C)nc12)Oc1ccccc1 |r| Show InChI InChI=1S/C33H45N6O11P/c1-16(2)31(41)48-25-23(15-45-51(44,50-21-12-10-9-11-13-21)38-19(7)33(43)46-18(5)6)47-30(26(25)49-32(42)17(3)4)39-14-22(28(35)40)24-27(34)36-20(8)37-29(24)39/h9-14,16-19,23,25-26,30H,15H2,1-8H3,(H2,35,40)(H,38,44)(H2,34,36,37)/t19-,23+,25+,26+,30+,51?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.57E+4	n/a	n/a	n/a	n/a
Chimerix, Inc.; The Regents of the University of Michigan US Patent					Assay Description Polymerase reactions (10 μL) were conducted for 60 minutes at 37° C. Nucleoside triphosphates (NTPs) were present at 100 μM each, with 0.05...				US Patent US9708359 (2017) BindingDB Entry DOI: 10.7270/Q22F7QGB
					More data for this Ligand-Target Pair