BDBM263087 US9708359, 141

SMILES: CC(C)OC(=O)[C@H](C)NP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(C(N)=O)c2c(N)nc(C)nc12

InChI Key: InChIKey=ZUDSPPUKUDIMIK-PYMYMTBYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 263087   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Norovirus Polymerase (Murine norovirus 1)	BDBM263087 (US9708359, 141) Show SMILES CC(C)OC(=O)[C@H](C)NP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(C(N)=O)c2c(N)nc(C)nc12 |r| Show InChI InChI=1S/C19H29N6O9P/c1-7(2)33-19(29)8(3)24-35(30,31)32-6-11-13(26)14(27)18(34-11)25-5-10(16(21)28)12-15(20)22-9(4)23-17(12)25/h5,7-8,11,13-14,18,26-27H,6H2,1-4H3,(H2,21,28)(H2,20,22,23)(H2,24,30,31)/t8-,11+,13+,14+,18+/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a
Chimerix, Inc.; The Regents of the University of Michigan US Patent					Assay Description Polymerase reactions (10 μL) were conducted for 60 minutes at 37° C. Nucleoside triphosphates (NTPs) were present at 100 μM each, with 0.05...				US Patent US9708359 (2017) BindingDB Entry DOI: 10.7270/Q22F7QGB
					More data for this Ligand-Target Pair