BDBM263099 US9708359, 20

SMILES: Cc1nc(N)c2c(cn([C@@H]3O[C@H](CO)[C@H]4OC(C)(C)O[C@@H]34)c2n1)C(N)=O

InChI Key: InChIKey=CWYRQUQKYBWPKC-ORXWAGORSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 263099   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Norovirus Polymerase (Murine norovirus 1)	BDBM263099 (US9708359, 20) Show SMILES Cc1nc(N)c2c(cn([C@@H]3O[C@H](CO)[C@H]4OC(C)(C)O[C@@H]34)c2n1)C(N)=O |r| Show InChI InChI=1S/C16H21N5O5/c1-6-19-12(17)9-7(13(18)23)4-21(14(9)20-6)15-11-10(8(5-22)24-15)25-16(2,3)26-11/h4,8,10-11,15,22H,5H2,1-3H3,(H2,18,23)(H2,17,19,20)/t8-,10-,11-,15-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Chimerix, Inc.; The Regents of the University of Michigan US Patent					Assay Description Polymerase reactions (10 μL) were conducted for 60 minutes at 37° C. Nucleoside triphosphates (NTPs) were present at 100 μM each, with 0.05...				US Patent US9708359 (2017) BindingDB Entry DOI: 10.7270/Q22F7QGB
					More data for this Ligand-Target Pair