BDBM263108 US9708359, 33

SMILES: Cc1nc(N)c2c(cn([C@@H]3O[C@H](COCc4ccccc4)[C@@H](O)[C@H]3O)c2n1)C(O)=O

InChI Key: InChIKey=ZRAHGJPDGJWQPS-NVQRDWNXSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 263108   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Norovirus Polymerase (Murine norovirus 1)	BDBM263108 (US9708359, 33) Show SMILES Cc1nc(N)c2c(cn([C@@H]3O[C@H](COCc4ccccc4)[C@@H](O)[C@H]3O)c2n1)C(O)=O |r| Show InChI InChI=1S/C20H22N4O6/c1-10-22-17(21)14-12(20(27)28)7-24(18(14)23-10)19-16(26)15(25)13(30-19)9-29-8-11-5-3-2-4-6-11/h2-7,13,15-16,19,25-26H,8-9H2,1H3,(H,27,28)(H2,21,22,23)/t13-,15-,16-,19-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Chimerix, Inc.; The Regents of the University of Michigan US Patent					Assay Description Polymerase reactions (10 μL) were conducted for 60 minutes at 37° C. Nucleoside triphosphates (NTPs) were present at 100 μM each, with 0.05...				US Patent US9708359 (2017) BindingDB Entry DOI: 10.7270/Q22F7QGB
					More data for this Ligand-Target Pair