BDBM263112 US9708359, 37

SMILES: CN(C)c1nc(C)nc2n(cc(C(N)=O)c12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

InChI Key: InChIKey=FOPRXCKBYQDKHC-ORXWAGORSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 263112   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Norovirus Polymerase (Murine norovirus 1)	BDBM263112 (US9708359, 37) Show SMILES CN(C)c1nc(C)nc2n(cc(C(N)=O)c12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C15H21N5O5/c1-6-17-13(19(2)3)9-7(12(16)24)4-20(14(9)18-6)15-11(23)10(22)8(5-21)25-15/h4,8,10-11,15,21-23H,5H2,1-3H3,(H2,16,24)/t8-,10-,11-,15-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Chimerix, Inc.; The Regents of the University of Michigan US Patent					Assay Description Polymerase reactions (10 μL) were conducted for 60 minutes at 37° C. Nucleoside triphosphates (NTPs) were present at 100 μM each, with 0.05...				US Patent US9708359 (2017) BindingDB Entry DOI: 10.7270/Q22F7QGB
					More data for this Ligand-Target Pair