BDBM263607 2-(tert-butyl)-4-chloro-5-((6-(3-fluoropropoxyl)pyridine-3-yl)methoxy)pyridazin-3(2H)-one::US9713651, 39
SMILES: CC(C)(C)n1ncc(OCc2ccc(OCCCF)nc2)c(Cl)c1=O
InChI Key: InChIKey=LRFJJHCPWOXDAP-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (Bos taurus) | BDBM263607 (2-(tert-butyl)-4-chloro-5-((6-(3-fluoropropoxyl)py...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Lantheus Medical Imaging, Inc. US Patent | Assay Description The procedure for determining catalytic activity of submitochondrial particles was adapted from Satoh et al. (e.g., see Satoh T, Miyoshi H, Sakamoto ... | US Patent US9713651 (2017) BindingDB Entry DOI: 10.7270/Q2RX9F2F | |||||||||||
More data for this Ligand-Target Pair |