BDBM264504 N?[(S)-2,3-dihydroxypropyl]-17-(5-fluoropyridin-3-yl)oestra-1,3,5(10),16-tetraene-3-carboxamide::US9714266, 33
SMILES: C[C@]12CC[C@H]3[C@@H](CCc4cc(ccc34)C(=O)NC[C@H](O)CO)[C@@H]1CC=C2c1cncc(F)c1
InChI Key: InChIKey=NRCOGFHQXSFRPO-LJQBLAKWSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aldo-keto-reductase family 1 member C3 (Homo sapiens (Human)) | BDBM264504![]() (N?[(S)-2,3-dihydroxypropyl]-17-(5-fluoropyridin-3-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | 7.0 | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat... | US Patent US9714266 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6V7W | |||||||||||
More data for this Ligand-Target Pair |