BDBM264761 US9718792, 17-B

SMILES: CC(CC1CC(=NO1)c1ccc(cc1F)C#CC1CC1)(C(=O)NO)S(C)(=O)=O

InChI Key: InChIKey=UIDUJUWXYOAOHP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 264761   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
UDP-3-O-acyl-GlcNAc deacetylase (LpxC) (Pseudomonas aeruginosa)	BDBM264761 (US9718792, 17-B) Show SMILES CC(CC1CC(=NO1)c1ccc(cc1F)C#CC1CC1)(C(=O)NO)S(C)(=O)=O |c:5| Show InChI InChI=1S/C19H21FN2O5S/c1-19(18(23)21-24,28(2,25)26)11-14-10-17(22-27-14)15-8-7-13(9-16(15)20)6-5-12-3-4-12/h7-9,12,14,24H,3-4,10-11H2,1-2H3,(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00100	n/a	n/a	n/a	n/a	7.5	25
Novartis AG US Patent					Assay Description The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...				US Patent US9718792 (2017) BindingDB Entry DOI: 10.7270/Q2XG9T4Z
					More data for this Ligand-Target Pair