BDBM265080 US10413550, Example 26::US9718793, 26

SMILES: CCNC(=O)c1noc(c1-c1ccc(cc1)N1CCNCC1)-c1cc(Cl)c(O)cc1O

InChI Key: InChIKey=MVNXERLMEBMAEV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 265080   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endoplasmin/Heat shock protein HSP 90-alpha/Heat shock protein HSP 90-beta/Heat shock protein, mitochondrial (Homo sapiens (Human)-Alligator mississippiensis (A...)	BDBM265080 (US10413550, Example 26 | US9718793, 26) Show SMILES CCNC(=O)c1noc(c1-c1ccc(cc1)N1CCNCC1)-c1cc(Cl)c(O)cc1O Show InChI InChI=1S/C22H23ClN4O4/c1-2-25-22(30)20-19(13-3-5-14(6-4-13)27-9-7-24-8-10-27)21(31-26-20)15-11-16(23)18(29)12-17(15)28/h3-6,11-12,24,28-29H,2,7-10H2,1H3,(H,25,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research US Patent					Assay Description (1) Greiner 384-well (Greiner 781101) or Costar 384-well flat-bottomed polystyrene multiwell plates (VWR). (2) Assay buffer of (a) 100 mM Tris...				US Patent US10413550 (2019) BindingDB Entry DOI: 10.7270/Q2C82CP2
					More data for this Ligand-Target Pair
Heat shock protein HSP 90-alpha (Homo sapiens (Human))	BDBM265080 (US10413550, Example 26 | US9718793, 26) Show SMILES CCNC(=O)c1noc(c1-c1ccc(cc1)N1CCNCC1)-c1cc(Cl)c(O)cc1O Show InChI InChI=1S/C22H23ClN4O4/c1-2-25-22(30)20-19(13-3-5-14(6-4-13)27-9-7-24-8-10-27)21(31-26-20)15-11-16(23)18(29)12-17(15)28/h3-6,11-12,24,28-29H,2,7-10H2,1H3,(H,25,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis (R&D) Ltd.; Cancer Research Technology Limited; The Institute of Cancer Research US Patent					Assay Description Fluorescence polarization {also known as fluorescence anisotropy} measures the rotation of a fluorescing species in solution, where the larger molecu...				US Patent US9718793 (2017) BindingDB Entry DOI: 10.7270/Q2SQ92DM
					More data for this Ligand-Target Pair