BDBM26627 (5Z)-3-{[4-(trifluoromethoxy)phenyl]methyl}-5-{[3-(trifluoromethyl)phenyl]methylidene}-1,3-thiazolidine-2,4-dione::thiazolidine-2,4-dione, 5a

SMILES: FC(F)(F)Oc1ccc(CN2C(=O)S\C(=C/c3cccc(c3)C(F)(F)F)C2=O)cc1

InChI Key: InChIKey=IZDAXLSKLAFJRU-DHDCSXOGSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26627   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM26627 ((5Z)-3-{[4-(trifluoromethoxy)phenyl]methyl}-5-{[3-...) Show SMILES FC(F)(F)Oc1ccc(CN2C(=O)S\C(=C/c3cccc(c3)C(F)(F)F)C2=O)cc1 Show InChI InChI=1S/C19H11F6NO3S/c20-18(21,22)13-3-1-2-12(8-13)9-15-16(27)26(17(28)30-15)10-11-4-6-14(7-5-11)29-19(23,24)25/h1-9H,10H2/b15-9-	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of South Carolina					Assay Description The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...				J Med Chem 52: 74-86 (2009) Article DOI: 10.1021/jm800937p BindingDB Entry DOI: 10.7270/Q2S180SF
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM26627 ((5Z)-3-{[4-(trifluoromethoxy)phenyl]methyl}-5-{[3-...) Show SMILES FC(F)(F)Oc1ccc(CN2C(=O)S\C(=C/c3cccc(c3)C(F)(F)F)C2=O)cc1 Show InChI InChI=1S/C19H11F6NO3S/c20-18(21,22)13-3-1-2-12(8-13)9-15-16(27)26(17(28)30-15)10-11-4-6-14(7-5-11)29-19(23,24)25/h1-9H,10H2/b15-9-	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	7.0	25
Medical University of South Carolina					Assay Description The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...				J Med Chem 52: 74-86 (2009) Article DOI: 10.1021/jm800937p BindingDB Entry DOI: 10.7270/Q2S180SF
					More data for this Ligand-Target Pair