BDBM26631 (5Z)-5-{[4-(propan-2-yl)phenyl]methylidene}-1,3-thiazolidine-2,4-dione::thiazolidine-2,4-dione, 9a

SMILES: CC(C)c1ccc(C=C2SC(O)=NC2=O)cc1

InChI Key: InChIKey=GXIDNNRIWNVXTL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26631   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM26631 ((5Z)-5-{[4-(propan-2-yl)phenyl]methylidene}-1,3-th...) Show SMILES CC(C)c1ccc(C=C2SC(O)=NC2=O)cc1 |w:7.6,c:11| Show InChI InChI=1S/C13H13NO2S/c1-8(2)10-5-3-9(4-6-10)7-11-12(15)14-13(16)17-11/h3-8H,1-2H3,(H,14,15,16)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of South Carolina					Assay Description The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...				J Med Chem 52: 74-86 (2009) Article DOI: 10.1021/jm800937p BindingDB Entry DOI: 10.7270/Q2S180SF
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM26631 ((5Z)-5-{[4-(propan-2-yl)phenyl]methylidene}-1,3-th...) Show SMILES CC(C)c1ccc(C=C2SC(O)=NC2=O)cc1 |w:7.6,c:11| Show InChI InChI=1S/C13H13NO2S/c1-8(2)10-5-3-9(4-6-10)7-11-12(15)14-13(16)17-11/h3-8H,1-2H3,(H,14,15,16)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	7.0	25
Medical University of South Carolina					Assay Description The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...				J Med Chem 52: 74-86 (2009) Article DOI: 10.1021/jm800937p BindingDB Entry DOI: 10.7270/Q2S180SF
					More data for this Ligand-Target Pair