BDBM26790 (3S,4S)-3-N-hydroxy-4-N-(4-{[2-(methylsulfanyl)-1H-1,3-benzodiazol-1-yl]methyl}benzene)pyrrolidine-3,4-dicarboxamide::benzimidazole analog., 16

SMILES: CSc1nc2ccccc2n1Cc1ccc(cc1)C(=O)N[C@@H]1CNC[C@@H]1C(=O)NO

InChI Key: InChIKey=XUGIQJJECDDGBH-DOTOQJQBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26790   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig))	BDBM26790 ((3S,4S)-3-N-hydroxy-4-N-(4-{[2-(methylsulfanyl)-1H...) Show SMILES CSc1nc2ccccc2n1Cc1ccc(cc1)C(=O)N[C@@H]1CNC[C@@H]1C(=O)NO |r| Show InChI InChI=1S/C21H23N5O3S/c1-30-21-24-16-4-2-3-5-18(16)26(21)12-13-6-8-14(9-7-13)19(27)23-17-11-22-10-15(17)20(28)25-29/h2-9,15,17,22,29H,10-12H2,1H3,(H,23,27)(H,25,28)/t15-,17+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	7.5	25
Bristol-Myers Squibb Company					Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...				Bioorg Med Chem Lett 18: 1577-82 (2008) Article DOI: 10.1016/j.bmcl.2008.01.075 BindingDB Entry DOI: 10.7270/Q2GM85NS
					More data for this Ligand-Target Pair