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SMILES: Cc1c(F)cccc1[C@@]1(Cc2cn(nc2C1)-c1ncccc1F)C(=O)NO

InChI Key: InChIKey=WKAMXVLNHDYKNP-IBGZPJMESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272093   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272093 ((S)-5-(3-Fluoro-2-methylphenyl)-2-(3-fluoropyridin...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cn(nc2C1)-c1ncccc1F)C(=O)NO |r| Show InChI InChI=1S/C19H16F2N4O2/c1-11-13(4-2-5-14(11)20)19(18(26)24-27)8-12-10-25(23-16(12)9-19)17-15(21)6-3-7-22-17/h2-7,10,27H,8-9H2,1H3,(H,24,26)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10457675 (2019) BindingDB Entry DOI: 10.7270/Q22J6F7J
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272093 ((S)-5-(3-Fluoro-2-methylphenyl)-2-(3-fluoropyridin...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cn(nc2C1)-c1ncccc1F)C(=O)NO |r| Show InChI InChI=1S/C19H16F2N4O2/c1-11-13(4-2-5-14(11)20)19(18(26)24-27)8-12-10-25(23-16(12)9-19)17-15(21)6-3-7-22-17/h2-7,10,27H,8-9H2,1H3,(H,24,26)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair