BDBM272116 (S)-2-Cyclopropyl-6-(3-fluoro-2-methylphenyl)-N- hydroxy-6,7-dihydro-5H-cyclopenta[d]pyrimidine-6- carboxamide::US10065948, 52::US10457675, Example 52

SMILES: Cc1c(F)cccc1[C@@]1(Cc2cnc(nc2C1)C1CC1)C(=O)NO

InChI Key: InChIKey=RBXLMMUKOIVVKT-SFHVURJKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272116 ((S)-2-Cyclopropyl-6-(3-fluoro-2-methylphenyl)-N- h...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnc(nc2C1)C1CC1)C(=O)NO |r| Show InChI InChI=1S/C18H18FN3O2/c1-10-13(3-2-4-14(10)19)18(17(23)22-24)7-12-9-20-16(11-5-6-11)21-15(12)8-18/h2-4,9,11,24H,5-8H2,1H3,(H,22,23)/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10457675 (2019) BindingDB Entry DOI: 10.7270/Q22J6F7J
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272116 ((S)-2-Cyclopropyl-6-(3-fluoro-2-methylphenyl)-N- h...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnc(nc2C1)C1CC1)C(=O)NO |r| Show InChI InChI=1S/C18H18FN3O2/c1-10-13(3-2-4-14(10)19)18(17(23)22-24)7-12-9-20-16(11-5-6-11)21-15(12)8-18/h2-4,9,11,24H,5-8H2,1H3,(H,22,23)/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair