BDBM272136 (S)-2-Cyclopropyl-6-(3-fluoro-2-methylphenyl)-N- hydroxy-5,6-dihydro-4H-cyclopenta[d]thiazole-6- carboxamide::US10065948, 72::US10457675, Example 72

SMILES: Cc1c(F)cccc1[C@@]1(CCc2nc(sc12)C1CC1)C(=O)NO

InChI Key: InChIKey=WNOUOJXJZAVXOA-QGZVFWFLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272136   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272136 ((S)-2-Cyclopropyl-6-(3-fluoro-2-methylphenyl)-N- h...) Show SMILES Cc1c(F)cccc1[C@@]1(CCc2nc(sc12)C1CC1)C(=O)NO |r| Show InChI InChI=1S/C17H17FN2O2S/c1-9-11(3-2-4-12(9)18)17(16(21)20-22)8-7-13-14(17)23-15(19-13)10-5-6-10/h2-4,10,22H,5-8H2,1H3,(H,20,21)/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10457675 (2019) BindingDB Entry DOI: 10.7270/Q22J6F7J
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272136 ((S)-2-Cyclopropyl-6-(3-fluoro-2-methylphenyl)-N- h...) Show SMILES Cc1c(F)cccc1[C@@]1(CCc2nc(sc12)C1CC1)C(=O)NO |r| Show InChI InChI=1S/C17H17FN2O2S/c1-9-11(3-2-4-12(9)18)17(16(21)20-22)8-7-13-14(17)23-15(19-13)10-5-6-10/h2-4,10,22H,5-8H2,1H3,(H,20,21)/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair