BDBM272137 (S)-6-(3-Fluoro-2-methylphenyl)-N-hydroxy-2-(o- tolyl)-5,6-dihydro-4H-cyclopenta[d]thiazole-6- carboxamide::US10065948, 73::US10457675, Example 73

SMILES: Cc1ccccc1-c1nc2CC[C@](C(=O)NO)(c2s1)c1cccc(F)c1C

InChI Key: InChIKey=BCXSCVXYWCEYON-OAQYLSRUSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272137   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272137 ((S)-6-(3-Fluoro-2-methylphenyl)-N-hydroxy-2-(o- to...) Show SMILES Cc1ccccc1-c1nc2CC[C@](C(=O)NO)(c2s1)c1cccc(F)c1C |r| Show InChI InChI=1S/C21H19FN2O2S/c1-12-6-3-4-7-14(12)19-23-17-10-11-21(18(17)27-19,20(25)24-26)15-8-5-9-16(22)13(15)2/h3-9,26H,10-11H2,1-2H3,(H,24,25)/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	143	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10457675 (2019) BindingDB Entry DOI: 10.7270/Q22J6F7J
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272137 ((S)-6-(3-Fluoro-2-methylphenyl)-N-hydroxy-2-(o- to...) Show SMILES Cc1ccccc1-c1nc2CC[C@](C(=O)NO)(c2s1)c1cccc(F)c1C |r| Show InChI InChI=1S/C21H19FN2O2S/c1-12-6-3-4-7-14(12)19-23-17-10-11-21(18(17)27-19,20(25)24-26)15-8-5-9-16(22)13(15)2/h3-9,26H,10-11H2,1-2H3,(H,24,25)/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	143	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair