BDBM272353 US10065950, Example 195
SMILES: COC[C@@H]1Cn2cc(-c3nnc(Cc4ccc(F)cc4)s3)c(=O)c(O)c2C(=O)N1C1CCC1
InChI Key: InChIKey=OQJUQDYAIUHQTR-INIZCTEOSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
inhibitory activity (Human immunodeficiency virus type 1 group M subtyp...) | BDBM272353 (US10065950, Example 195) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | n/a | 25 |
Japan Tobacco Inc. US Patent | Assay Description The donor DNA was diluted with TE buffer to 20 nM, of which 50 μL was added to each well of streptavidin-coated black plate (manufactured by PIA... | US Patent US10065950 (2018) BindingDB Entry DOI: 10.7270/Q2RN39V2 | |||||||||||
More data for this Ligand-Target Pair |