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BDBM272482 US10065950, Example 330

SMILES: CCN1[C@H](C)Cn2cc(-c3ncc(Cc4ccc(F)cc4)s3)c(=O)c(O)c2C1=O

InChI Key: InChIKey=MEQZIWTVCQBZCM-GFCCVEGCSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 272482   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
inhibitory activity


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM272482
PNG
(US10065950, Example 330)
Show SMILES CCN1[C@H](C)Cn2cc(-c3ncc(Cc4ccc(F)cc4)s3)c(=O)c(O)c2C1=O |r|
Show InChI InChI=1S/C21H20FN3O3S/c1-3-25-12(2)10-24-11-16(18(26)19(27)17(24)21(25)28)20-23-9-15(29-20)8-13-4-6-14(22)7-5-13/h4-7,9,11-12,27H,3,8,10H2,1-2H3/t12-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.40n/an/an/an/an/a25



Japan Tobacco Inc.

US Patent


Assay Description
The donor DNA was diluted with TE buffer to 20 nM, of which 50 μL was added to each well of streptavidin-coated black plate (manufactured by PIA...

US Patent US10065950 (2018)


BindingDB Entry DOI: 10.7270/Q2RN39V2
More data for this
Ligand-Target Pair