BDBM275096 US10221195, Example 38::US9879032, Example 38

SMILES: COc1ccc(Cl)cc1S(=O)(=O)Nc1cnc2OCCN(c3ccccn3)C(=O)c2c1

InChI Key: InChIKey=NRZVEFQWGJRHCN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 275096   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM275096 (US10221195, Example 38 | US9879032, Example 38) Show SMILES COc1ccc(Cl)cc1S(=O)(=O)Nc1cnc2OCCN(c3ccccn3)C(=O)c2c1 Show InChI InChI=1S/C20H17ClN4O5S/c1-29-16-6-5-13(21)10-17(16)31(27,28)24-14-11-15-19(23-12-14)30-9-8-25(20(15)26)18-4-2-3-7-22-18/h2-7,10-12,24H,8-9H2,1H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24.4	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Company, Limited; Sanford Burnham Prebys Medical Discovery Institute US Patent					Assay Description COS1 cells (DS Pharma Biomedical Co., Ltd.) were transfected with human TNAP (OriGene Technologies, Inc.) using Lipofectamine LTX & Plus reagent (Inv...				US Patent US10221195 (2019) BindingDB Entry DOI: 10.7270/Q2QZ2D83
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM275096 (US10221195, Example 38 | US9879032, Example 38) Show SMILES COc1ccc(Cl)cc1S(=O)(=O)Nc1cnc2OCCN(c3ccccn3)C(=O)c2c1 Show InChI InChI=1S/C20H17ClN4O5S/c1-29-16-6-5-13(21)10-17(16)31(27,28)24-14-11-15-19(23-12-14)30-9-8-25(20(15)26)18-4-2-3-7-22-18/h2-7,10-12,24H,8-9H2,1H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24.4	n/a	n/a	n/a	n/a	n/a	25
Daiichi Sankyo Company, Limited; Sandford Burnham Prebys Medical Discovery Institute US Patent					Assay Description COS 1 cells (DS Pharma Biomedical Co., Ltd.) were transfected with human TNAP (OriGene Technologies, Inc.) using Lipofectamine LTX & Plus reagent (In...				US Patent US9879032 (2018) BindingDB Entry DOI: 10.7270/Q2F76FKB
					More data for this Ligand-Target Pair