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SMILES: CNS(=O)(=O)NC(=O)c1cc(Cl)c(Oc2cnc(Cl)c(Cl)c2)cc1F

InChI Key: InChIKey=BOQBVZPWCKVLSN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275820   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM275820
PNG
(5-chloro-4-((5,6- dichloropyridin-3- yl)oxy)-2-flu...)
Show SMILES CNS(=O)(=O)NC(=O)c1cc(Cl)c(Oc2cnc(Cl)c(Cl)c2)cc1F
Show InChI InChI=1S/C13H9Cl3FN3O4S/c1-18-25(22,23)20-13(21)7-3-8(14)11(4-10(7)17)24-6-2-9(15)12(16)19-5-6/h2-5,18H,1H3,(H,20,21)
PDB

KEGG

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PC cid
PC sid
UniChem
US Patent
n/an/a 628n/an/an/an/a7.425



GENENTECH, INC.; XENON PHARMACEUTICALS INC.

US Patent


Assay Description
Preparation of membranes containing recombinantly expressed sodium channels: Frozen recombinant cell pellets were thawed on ice and diluted to 4 time...

US Patent US10071957 (2018)


BindingDB Entry DOI: 10.7270/Q2J1056P
More data for this
Ligand-Target Pair