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BDBM280300 US10029993, Example 135

SMILES: CC[C@@H](O)C(=O)N1CCC(CC1)NC(=O)CN1CCN(CC1)c1nncc(n1)-c1ccc(F)cc1

InChI Key: InChIKey=GRXDFUYNIHTKNU-OAQYLSRUSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 280300   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cytochrome P450 11B2 (CYP11B2)


(Homo sapiens (Human))		BDBM280300
PNG
(US10029993, Example 135)
Show SMILES CC[C@@H](O)C(=O)N1CCC(CC1)NC(=O)CN1CCN(CC1)c1nncc(n1)-c1ccc(F)cc1 |r|
Show InChI InChI=1S/C24H32FN7O3/c1-2-21(33)23(35)31-9-7-19(8-10-31)27-22(34)16-30-11-13-32(14-12-30)24-28-20(15-26-29-24)17-3-5-18(25)6-4-17/h3-6,15,19,21,33H,2,7-14,16H2,1H3,(H,27,34)/t21-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 12n/an/an/an/a7.425



MITSUBISHI TANABE PHARMA CORPORATION

US Patent


Assay Description
The pcDNA3.1-human CYP11B2 plasmid was transfected into a Chinese hamster lung fibroblast V79 cell line to produce a cell line stably expressing huma...

US Patent US10029993 (2018)


BindingDB Entry DOI: 10.7270/Q2V40X6M
More data for this
Ligand-Target Pair