BDBM280330 US10029993, Example 244

SMILES: Cc1ccccc1-c1cnnc(n1)C1CCCN(C1)c1cnccn1

InChI Key: InChIKey=LGMCHIKSHBMGBJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 280330   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM280330 (US10029993, Example 244) Show SMILES Cc1ccccc1-c1cnnc(n1)C1CCCN(C1)c1cnccn1 Show InChI InChI=1S/C19H20N6/c1-14-5-2-3-7-16(14)17-11-22-24-19(23-17)15-6-4-10-25(13-15)18-12-20-8-9-21-18/h2-3,5,7-9,11-12,15H,4,6,10,13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.4	25
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The pcDNA3.1-human CYP11B2 plasmid was transfected into a Chinese hamster lung fibroblast V79 cell line to produce a cell line stably expressing huma...				US Patent US10029993 (2018) BindingDB Entry DOI: 10.7270/Q2V40X6M
					More data for this Ligand-Target Pair