BDBM281767 2-(3-(1H-pyrrolo[2,3-b]pyridin- 3-yl)benzylamino)-N-(4- fluorobenzyl)nicotinamide::US10030016, Example 1.6

SMILES: Fc1ccc(CNC(=O)c2cccnc2NCc2cccc(c2)-c2c[nH]c3ncccc23)cc1

InChI Key: InChIKey=LZRXHNBORXWYRR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 281767   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-phosphoinositide-dependent protein kinase 1 [51-359] (Homo sapiens (Human))	BDBM281767 (2-(3-(1H-pyrrolo[2,3-b]pyridin- 3-yl)benzylamino)-...) Show SMILES Fc1ccc(CNC(=O)c2cccnc2NCc2cccc(c2)-c2c[nH]c3ncccc23)cc1 Show InChI InChI=1S/C27H22FN5O/c28-21-10-8-18(9-11-21)15-33-27(34)23-7-3-13-30-26(23)31-16-19-4-1-5-20(14-19)24-17-32-25-22(24)6-2-12-29-25/h1-14,17H,15-16H2,(H,29,32)(H,30,31)(H,33,34)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals, Inc.; Millenium Pharmaceuticals, Inc. US Patent					Assay Description PDK1 (amino acids 51-359) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) were expressed as N-terminally tagged GST fusi...				US Patent US10030016 (2018) BindingDB Entry DOI: 10.7270/Q2S46V16
					More data for this Ligand-Target Pair