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SMILES: OC1(CS(=O)(=O)c2ccc(Oc3cc(F)cc(c3)C#N)c(C#N)c12)C(F)(F)F

InChI Key: InChIKey=FRUVJOROVNFVLO-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 282760   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor A


(Homo sapiens (Human))		BDBM282760
PNG
(US9884843, Compound 104)
Show SMILES OC1(CS(=O)(=O)c2ccc(Oc3cc(F)cc(c3)C#N)c(C#N)c12)C(F)(F)F
Show InChI InChI=1S/C17H8F4N2O4S/c18-10-3-9(6-22)4-11(5-10)27-13-1-2-14-15(12(13)7-23)16(24,17(19,20)21)8-28(14,25)26/h1-5,24H,8H2
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PC cid
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US Patent
n/an/a 6.30E+3n/an/an/an/a7.5n/a



PELOTON THERAPEUTICS, INC.

US Patent


Assay Description
The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...

US Patent US9884843 (2018)


BindingDB Entry DOI: 10.7270/Q2HQ41Z0
More data for this
Ligand-Target Pair