null
SMILES: CC1(C)C[C@]2(C[C@H]2C(=O)Nc2cc(ccc2CCCC(O)=O)C#N)c2cc(ccc12)-c1cccnc1
InChI Key: InChIKey=RSCZKBTVWRNMLT-SETSBSEESA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human)) | BDBM285513 (4-[4-Cyano-2-({[(1S,2R)-3′,3′-dimethyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | 25 |
ONO PHARMACEUTICAL CO., LTD. US Patent | Assay Description EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer... | US Patent US10077247 (2018) BindingDB Entry DOI: 10.7270/Q22J6DWN | |||||||||||
More data for this Ligand-Target Pair |