BDBM28707 2-methyl-2-phenoxypropanoic acid, 27::2-methyl-2-{4-[(N-methyl{4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}formamido)methyl]phenoxy}propanoic acid
SMILES: CN(Cc1ccc(OC(C)(C)C(O)=O)cc1)C(=O)c1sc(nc1C)-c1ccc(cc1)C(F)(F)F
InChI Key: InChIKey=LNPYUCKFDARPOI-UHFFFAOYSA-N
Data: 3 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human)) | BDBM28707![]() (2-methyl-2-phenoxypropanoic acid, 27 | 2-methyl-2-...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 240 | n/a | n/a | n/a | n/a |
GSK | Assay Description The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ... | J Med Chem 50: 685-95 (2007) Article DOI: 10.1021/jm058056x BindingDB Entry DOI: 10.7270/Q2RN3669 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM28707![]() (2-methyl-2-phenoxypropanoic acid, 27 | 2-methyl-2-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
GSK | Assay Description The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ... | J Med Chem 50: 685-95 (2007) Article DOI: 10.1021/jm058056x BindingDB Entry DOI: 10.7270/Q2RN3669 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human)) | BDBM28707![]() (2-methyl-2-phenoxypropanoic acid, 27 | 2-methyl-2-...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
GSK | Assay Description The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ... | J Med Chem 50: 685-95 (2007) Article DOI: 10.1021/jm058056x BindingDB Entry DOI: 10.7270/Q2RN3669 | |||||||||||
More data for this Ligand-Target Pair |