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SMILES: FC(F)(F)COc1cc(cnn1)-c1nc2ccc(cc2n1C1CC1)C#N

InChI Key: InChIKey=RKMYVHHXVOUUMK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 287740   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287740 (US10085984, Example 118 | US11040034, Ex. No. 118) Show SMILES FC(F)(F)COc1cc(cnn1)-c1nc2ccc(cc2n1C1CC1)C#N Show InChI InChI=1S/C17H12F3N5O/c18-17(19,20)9-26-15-6-11(8-22-24-15)16-23-13-4-1-10(7-21)5-14(13)25(16)12-2-3-12/h1,4-6,8,12H,2-3,9H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Viamet Pharmaceuticals (Bermuda), Ltd. US Patent					Assay Description V79-4 cells expressing recombinant andrenodoxin and andrenodoxin reductase with either recombinant human CYP11B2 or CYP11B1 were prepared according t...				US Patent US10085984 (2018) BindingDB Entry DOI: 10.7270/Q2542QM2
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM287740 (US10085984, Example 118 | US11040034, Ex. No. 118) Show SMILES FC(F)(F)COc1cc(cnn1)-c1nc2ccc(cc2n1C1CC1)C#N Show InChI InChI=1S/C17H12F3N5O/c18-17(19,20)9-26-15-6-11(8-22-24-15)16-23-13-4-1-10(7-21)5-14(13)25(16)12-2-3-12/h1,4-6,8,12H,2-3,9H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287740 (US10085984, Example 118 | US11040034, Ex. No. 118) Show SMILES FC(F)(F)COc1cc(cnn1)-c1nc2ccc(cc2n1C1CC1)C#N Show InChI InChI=1S/C17H12F3N5O/c18-17(19,20)9-26-15-6-11(8-22-24-15)16-23-13-4-1-10(7-21)5-14(13)25(16)12-2-3-12/h1,4-6,8,12H,2-3,9H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM287740 (US10085984, Example 118 | US11040034, Ex. No. 118) Show SMILES FC(F)(F)COc1cc(cnn1)-c1nc2ccc(cc2n1C1CC1)C#N Show InChI InChI=1S/C17H12F3N5O/c18-17(19,20)9-26-15-6-11(8-22-24-15)16-23-13-4-1-10(7-21)5-14(13)25(16)12-2-3-12/h1,4-6,8,12H,2-3,9H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Viamet Pharmaceuticals (Bermuda), Ltd. US Patent					Assay Description V79-4 cells expressing recombinant andrenodoxin and andrenodoxin reductase with either recombinant human CYP11B2 or CYP11B1 were prepared according t...				US Patent US10085984 (2018) BindingDB Entry DOI: 10.7270/Q2542QM2
					More data for this Ligand-Target Pair