BDBM28816 5-methyl-N-(4-methylphenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine::triazolopyrimidine-based compound, DSM97

SMILES: Cc1ccc(Nc2cc(C)nc3ncnn23)cc1

InChI Key: InChIKey=DSIFRBWQRQZHCP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate Dehydrogenase (DHODH) (Plasmodium berghei)	BDBM28816 (5-methyl-N-(4-methylphenyl)-[1,2,4]triazolo[1,5-a]...) Show SMILES Cc1ccc(Nc2cc(C)nc3ncnn23)cc1 Show InChI InChI=1S/C13H13N5/c1-9-3-5-11(6-4-9)17-12-7-10(2)16-13-14-8-15-18(12)13/h3-8,17H,1-2H3	KEGG GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Washington at Seattle					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Med Chem 52: 1864-72 (2009) Article DOI: 10.1021/jm801343r BindingDB Entry DOI: 10.7270/Q2QN653C
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum (isolate 3D7))	BDBM28816 (5-methyl-N-(4-methylphenyl)-[1,2,4]triazolo[1,5-a]...) Show SMILES Cc1ccc(Nc2cc(C)nc3ncnn23)cc1 Show InChI InChI=1S/C13H13N5/c1-9-3-5-11(6-4-9)17-12-7-10(2)16-13-14-8-15-18(12)13/h3-8,17H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	8.0	20
University of Washington at Seattle					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Med Chem 52: 1864-72 (2009) Article DOI: 10.1021/jm801343r BindingDB Entry DOI: 10.7270/Q2QN653C
					More data for this Ligand-Target Pair