BDBM28839 5-methyl-N-[4-methyl-3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine::triazolopyrimidine-based compound, DSM122

SMILES: Cc1cc(Nc2ccc(C)c(c2)C(F)(F)F)n2ncnc2n1

InChI Key: InChIKey=ZEPMPJCWXKPMQM-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 28839   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum (isolate 3D7))	BDBM28839 (5-methyl-N-[4-methyl-3-(trifluoromethyl)phenyl]-[1...) Show SMILES Cc1cc(Nc2ccc(C)c(c2)C(F)(F)F)n2ncnc2n1 Show InChI InChI=1S/C14H12F3N5/c1-8-3-4-10(6-11(8)14(15,16)17)21-12-5-9(2)20-13-18-7-19-22(12)13/h3-7,21H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Washington at Seattle					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Med Chem 52: 1864-72 (2009) Article DOI: 10.1021/jm801343r BindingDB Entry DOI: 10.7270/Q2QN653C
					More data for this Ligand-Target Pair
Dihydroorotate Dehydrogenase (DHODH) (Homo sapiens (Human))	BDBM28839 (5-methyl-N-[4-methyl-3-(trifluoromethyl)phenyl]-[1...) Show SMILES Cc1cc(Nc2ccc(C)c(c2)C(F)(F)F)n2ncnc2n1 Show InChI InChI=1S/C14H12F3N5/c1-8-3-4-10(6-11(8)14(15,16)17)21-12-5-9(2)20-13-18-7-19-22(12)13/h3-7,21H,1-2H3	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Washington at Seattle					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Med Chem 52: 1864-72 (2009) Article DOI: 10.1021/jm801343r BindingDB Entry DOI: 10.7270/Q2QN653C
					More data for this Ligand-Target Pair
Dihydroorotate Dehydrogenase (DHODH) (Plasmodium berghei)	BDBM28839 (5-methyl-N-[4-methyl-3-(trifluoromethyl)phenyl]-[1...) Show SMILES Cc1cc(Nc2ccc(C)c(c2)C(F)(F)F)n2ncnc2n1 Show InChI InChI=1S/C14H12F3N5/c1-8-3-4-10(6-11(8)14(15,16)17)21-12-5-9(2)20-13-18-7-19-22(12)13/h3-7,21H,1-2H3	KEGG GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Washington at Seattle					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Med Chem 52: 1864-72 (2009) Article DOI: 10.1021/jm801343r BindingDB Entry DOI: 10.7270/Q2QN653C
					More data for this Ligand-Target Pair